Table 2.
Changes in pupil characteristics before and after opioid administration
| Parameter | LOC | Remifentanil Ce 5 ng mL−1 | P‐valuea |
|---|---|---|---|
| Baseline pupil diameter (mm) | 4.00 [IQR 3.30‐4.50] | 1.90 [IQR 1.70‐2.00] | <.0005 |
| Stimulation intensity (mA) | 30.00 [IQR 20.00‐40.00] | 60.00 [IQR 60.00‐60.00] | <.0005 |
| PDRA (mm) | 1.11 [IQR 0.91‐1.47] | 0.16 [IQR 0.11‐0.23] | <.0005 |
| Pupil variation (%) | 28 [IQR 21‐39] | 8 [IQR 6‐12] | <.0005 |
| PPI score | 8 [IQR 7‐9] | 2 [IQR 1‐2] | <.0005 |
PDRA, pupillary dilation reflex amplitude; PPI, pupillary pain index.
Data are expressed as the overall median and interquartile range [IQR]. Loss of consciousness (LOC) and remifentanil Ce 5 ng mL−1 are reported for the first and second PDR assessment, respectively.
a
Statistically significant for P < .05.