Table 2.

The changes in expression of selected signaling molecules induced by MM3 in cultures of Jurkat cells. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) was used as a housekeeping gene to normalize values obtained for the target genes. The values presented in the table reflect relative fold changes in response of the cells to the MM3 compound, when the GAPDH gene expression was a control and assumed as equal to one.

Signaling Molecule	MM3 (50 μM)
Bcl-2	0.5
Casp-3	20.6
Casp-7	16.0
Casp-8	50.7
Casp-9	2.7
Fas	7.8
NF-κB1	50.1
p53	0