Solvent |
Water |
Negative |
Main source of contamination |
- |
[20] |
Ethanol |
Positive |
Antimicrobial agent |
Ethanol (more than 30%) |
Thickener and emulsifiers based on lipids |
- |
- |
Fats, oils, waxes |
Surfactants |
Cationic |
Positive |
Perturbation of cell membranes or increase in membrane porosity which also facilitates penetration of other antimicrobial substances |
Alkylamines, quaternary ammonium compounds |
[20] |
Anionic |
Sulfates, sulfonates and carboxylates |
Amphoteric |
Alkylamidobetain and alkylamidoglycinate |
Non-ionic |
Fatty acids monoethanolamides, ethoxylated fatty alcohols and alkyl polyglucosides |
Humectants |
Positive |
At concentrations of 5 to 10%, they can effectively reduce the amount of biologically available water. |
Sugars (sorbitol), glycerol and gylcol |
[20] |
Gelling agents |
Positive |
Antimicrobial agent and reduction of biologically available water |
Polyacrylic acids and hydroxypropyl methylcellulose |
[20,172] |
Emollients |
Negative |
Promote the growth of microorganisms |
Silicon derivatives, proteins (milk proteins and albumin hydrolyzate) |
[20] |
Plants extracts and mineral raw materials |
Positive or negative |
Positive: polyphenols can exert antibacterial effect; Negative: source of contamination especially for spores, mycotoxins and Clostridium |
Melissa officinalis extract, rosmarinic acid and phenylethyl alcohol |
[20,100] |