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. 2018 Jun 28;23(7):1571. doi: 10.3390/molecules23071571

Table 2.

Influence of some cosmetic constituents on preservation.

Component Influence Effects Example References
Solvent Water Negative Main source of contamination - [20]
Ethanol Positive Antimicrobial agent Ethanol (more than 30%)
Thickener and emulsifiers based on lipids - - Fats, oils, waxes
Surfactants Cationic Positive Perturbation of cell membranes or increase in membrane porosity which also facilitates penetration of other antimicrobial substances Alkylamines, quaternary ammonium compounds [20]
Anionic Sulfates, sulfonates and carboxylates
Amphoteric Alkylamidobetain and alkylamidoglycinate
Non-ionic Fatty acids monoethanolamides, ethoxylated fatty alcohols and alkyl polyglucosides
Humectants Positive At concentrations of 5 to 10%, they can effectively reduce the amount of biologically available water. Sugars (sorbitol), glycerol and gylcol [20]
Gelling agents Positive Antimicrobial agent and reduction of biologically available water Polyacrylic acids and hydroxypropyl methylcellulose [20,172]
Emollients Negative Promote the growth of microorganisms Silicon derivatives, proteins (milk proteins and albumin hydrolyzate) [20]
Plants extracts and mineral raw materials Positive or negative Positive: polyphenols can exert antibacterial effect; Negative: source of contamination especially for spores, mycotoxins and Clostridium Melissa officinalis extract, rosmarinic acid and phenylethyl alcohol [20,100]