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. 2018 May 2;23(5):1062. doi: 10.3390/molecules23051062

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Treatment with TRYP suppressed the expression of p-STAT3, magnification ×400. (A) Immunohistochemistry result of control group with expressing p-STAT3 only. (B) The expression level of p-STAT3 increased sharply and both crypts and goblet cells disappeared. (C) Immunohistochemistry result of sulfasalazine control. (D–F) The expression level of p-STAT3 with different concentrations of TRYP treatment. (G) The column heights represented the positively stained cell rates. Error bars represented means ± SEM of n = 3, ** p < 0.01 compared with colitis.