Table 3.
AChE and BuChE inhibitory activities of some alkaloids identified in the aerial parts of R. splendens (T) and the reference compound galanthamine. Values are expressed as IC50 (μg/mL).
| Alkaloid | AChE | BuChE |
|---|---|---|
| 11-hydroxyvittatine (20a) | 122.17 ± 22.03 | >200 |
| lycorine (9) | 101.70 ± 23.79 | >200 |
| 8-O-demethylmaritidine (16) | 113.21 ± 8.21 | 127.87 ± 2.45 |
| hamayne (20b) | 135.09 ± 15.33 | 48.40 ± 1.13 |
| deacetylcantabricine (17) | >200 | >200 |
| haemanthamine (18a) | 184.68 ± 11.58 | >200 |
| galanthamine (28) | 0.48 ± 0.07 | 3.70 ± 0.24 |