Table 1.
Inhibition of NO production in RAW264.7 macrophages by alkaloids 1–10 a.
| Compounds | IC50 (µM) | Compounds | IC50 (µM) |
|---|---|---|---|
| 1 | >50 | 6 | 31.92 ± 0.01 * |
| 2 | >50 | 7 | 25.16 ± 0.41 * |
| 3 | >50 | 8 | >50 |
| 4 | >50 | 9 | >50 |
| 5 | >50 | 10 | 6.28 ± 0.45 * |
| Dexamethasone b | 0.009 ± 0.001 * |
a The inhibitory activities are presented as the concentration (μM) giving 50% inhibition (IC50) relative to the vehicle control, and the results are the mean of three replications. b Positive control. The data are presented as the mean ± SEM (n = 3) of three independent experiments. * p < 0.05 vs. the LPS-treated control group.