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LSD1 and MAO inhibitory activities of peptides 2a–c.
| Compound | IC50 (µM) 1 | ||
|---|---|---|---|
| LSD1 | MAO-A | MAO-B | |
| PCPA | 16.5 ± 1.9 | 6.00 ± 1.38 | 6.54 ± 0.51 |
| 1 | 0.126 ± 0.002 | >10 | >10 |
| 2a | 0.0891 ± 0.0053 | >10 | >10 |
| 2b | 0.0584 ± 0.0025 | >10 | >10 |
| 2c | 0.0724 ± 0.0040 | >10 | >10 |
1 Values are means ± S.D. of at least three experiments.
