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Inhibition of 11 β-HSD1 activity by C. telenitida library molecules. Sub-fractions 1 to 10 were obtained after fractionation of the primary fraction DE16. Data represent mean ± S.D. from three independent replicates. Rx: Positive control, microsomal 11β-HSD1 reaction. Rx(−): Negative control, reaction assay minus NADPH. The dashed line corresponds to a statistically significant level of inhibition.
