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. 2018 Jun 8;23(6):1382. doi: 10.3390/molecules23061382

Table 1.

Cytotoxic activity of the compounds 219 against proliferation of U87MG cells.

Esters Amides
Compound IC50 (μg/mL) Compound IC50 (μg/mL)
2 85.129 ± 0.78 14 13.196 ± 0.32
3 100.030 ± 1.12 15 33.128 ± 0.41
4 78.393 ± 0.69 16 22.741 ± 0.34
5 57.871 ± 0.71 17 22.654 ± 0.39
6 31.666 ± 0.48 18 43.396 ± 0.48
7 34.926 ± 0.54 19 36.072 ± 0.44
8 50.077 ± 0.62
9 81.433 ± 0.55
10 2.579 ± 0.35
11 26.701 ± 0.47
12 24.786 ± 0.37
13 30.336 ± 0.35

Positive control (paclitaxel): IC50: 2.119 ± 0.35 μg/mL.