Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Docking analysis of the most active (IC50 2.5 µM) compound 9, (A,A′) and the less active, (IC50 156.25 µM) compound 11 (B,B′) to the active site of the rat 15-LOX structure PDB ID: 1LOX (target box 35). Green: hydrogen bond interactions, Blue: polar interactions, yellow: pi interactions, brown: hydrophobic interactions.
