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Docking analysis of the most active (IC50 2.5 µM) compound, 9, (A,A′) and the less active, (IC50 156.25 µM) compound 11 (B,B′) with the active site of the human 5-LOX structure PDB ID: 3V99 (target box 30). Green: hydrogen bond interactions, blue: polar interactions, yellow: pi interactions, brown: hydrophobic interactions.
