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. 2018 Jul 3;23(7):1621. doi: 10.3390/molecules23071621

Table 2.

Prediction of the biological activity spectra of the designed compounds.

graphic file with name molecules-23-01621-i018.jpg

No. R2 Predicted Activity Pa
1 graphic file with name molecules-23-01621-i019.jpg Systemic lupus erythematosus treatment 0.905
Lipoxygenase inhibitor 0.846
Transcription factor inhibitor 0.768
Immunosuppressant 0.727
Lipid peroxidase inhibitor 0.682
Antiulcerative 0.674
2 graphic file with name molecules-23-01621-i020.jpg Lipoxygenase inhibitor 0.879
Systemic lupus erythematosus treatment 0.72
Immunosuppressant 0.726
Antineoplastic 0.696
Antiinflammatory 0.645
Lipid peroxidase inhibitor… 0.6
3 graphic file with name molecules-23-01621-i021.jpg Antiulcerative 0.748
Lipoxygenase inhibitor 0.743
Immunosuppressant 0.72
Systemic lupus erythematosus treatment 0.662
Antiinflammatory 0.632
Lipid peroxidase inhibitor 0.601
Antineoplastic… 0.639
4 graphic file with name molecules-23-01621-i022.jpg Lipoxygenase inhibitor 0.808
Antiulcerative 0.794
Transcription factor inhibitor 0.76
Systemic lupus erythematosus treatment 0.734
Immunosuppressant 0.706
Lipid peroxidase inhibitor 0.696
5 graphic file with name molecules-23-01621-i023.jpg Immunosuppressant 0.745
Lipoxygenase inhibitor 0.716
Antiulcerative 0.689
Systemic lupus erythematosus treatment 0.631
Antiinflammatory 0.616
Transcription factor inhibitor 0.594
Antineoplastic… 0.581
6 graphic file with name molecules-23-01621-i024.jpg Lipoxygenase inhibitor 0.875
Antiulcerative 0.799
Transcription factor inhibitor 0.753
Immunosuppressant 0.731
Antiinflammatory 0.692
Systemic lupus erythematosus treatment 0.587
Antineoplastic 0.609
7 graphic file with name molecules-23-01621-i025.jpg Antiulcerative 0.765
Lipoxygenase inhibitor 0.726
Transcription factor inhibitor 0.726
Immunosuppressant 0.716
Systemic lupus erythematosus treatment 0.699
Mediator release inhibitor 0.642
8 graphic file with name molecules-23-01621-i026.jpg Transcription factor inhibitor 0.751
Antiulcerative 0.709
Immunosuppressant 0.7
Systemic lupus erythematosus treatment 0.689
Mediator release inhibitor 0.662
Lipoxygenase inhibitor 0.661
9 graphic file with name molecules-23-01621-i027.jpg Antiulcerative 0.825
Lipoxygenase inhibitor 0.716
Transcription factor inhibitor 0.7
Immunosuppressant 0.688
Systemic lupus erythematosus treatment 0.615
Mediator release inhibitor 0.609
10 graphic file with name molecules-23-01621-i028.jpg Lipoxygenase inhibitor 0.774
Systemic lupus erythematosus treatment 0.746
Lipid peroxidase inhibitor 0.722
Immunosuppressant 0.7
Antiulcerative 0.679
Transcription factor inhibitor 0.673
11 graphic file with name molecules-23-01621-i029.jpg Lipoxygenase inhibitor 0.809
Lipid peroxidase inhibitor 0.698
Systemic lupus erythematosus treatment 0.688
Immunosuppressant 0.687
Antineoplastic 0.674
Antiulcerative 0.63
Apoptosis agonist... 0.615
12 graphic file with name molecules-23-01621-i030.jpg Antiulcerative 0.748
Lipoxygenase inhibitor 0.743
Immunosuppressant 0.72
Systemic lupus erythematosus treatment 0.662
Antiinflammatory 0.632
Lipid peroxidase inhibitor 0.601
Antineoplastic... 0.639
13 graphic file with name molecules-23-01621-i031.jpg Antiulcerative 0.748
Lipoxygenase inhibitor 0.743
Immunosuppressant 0.72
Systemic lupus erythematosus treatment 0.662
Antiinflammatory 0.632
Lipid peroxidase inhibitor 0.601
Antineoplastic... 0.639
14 graphic file with name molecules-23-01621-i032.jpg Antiulcerative 0.748
Lipoxygenase inhibitor 0.743
Immunosuppressant 0.72
Systemic lupus erythematosus treatment 0.662
Antiinflammatory 0.632
Lipid peroxidase inhibitor 0,601
Antineoplastic... 0.639
15 graphic file with name molecules-23-01621-i033.jpg Systemic lupus erythematosus treatment 0.791
Immunosuppressant 0.715
Lipoxygenase inhibitor 0.697
Transcription factor inhibitor 0.699
Antiinflammatory 0.656
Antineoplastic 0.664
Antiulcerative 0.625
16 graphic file with name molecules-23-01621-i034.jpg Lipoxygenase inhibitor 0.732
Immunosuppressant 0.714
Antineoplastic 0.692
Antiinflammatory 0.625
Systemic lupus erythematosus treatment 0.583
Apoptosis agonist 0.576
Antiulcerative 0.501