Table 6.

Results of docking analysis to the sLOX structure 1YGE and to human 5-LOX structure 3O8Y using different target center and box dimensions.

Free Binding Energy (Kcal/mole)
Comp.	Soybean sLOX 1YGE					Human 5-LOX 3O8Y					IC50
	Center: x: 26.37, y: 42.69, z: 12.36			Center: x: 20.37, y: 46.69, z: 8.36		Center: x: 8.59, y: 22.65, z: −1.02			Center: x: −3.57, y: 17.66, z: 8.36	Center: x: −12.50, y: 75.50, z: 0.50
	Box 20	Box 30	Box 35	Box 37 × 27 × 22	Box 36 × 20 × 20	Box 20	Box 30	Box 35	Box 20 × 25 × 20	Box 35 × 25 × 27
2			−7.11			−7.42					22.50
4			−7.00								31.25
5	+90.68		−8.20				−5.84				22.50
8			−7.83								90.00
9	+90.14	−6.34	−8.26	−5.68	−1.08	−8.28	−7.77	−8.25	−5.49	−6.09	2.50
11	−95.16	−6.41	−6.24	−6.01	+5.37	−8.09	−7.77	−6.51	−5.11	−6.63	156.25
13			−7.75				−7.57	−6.75			25.00
14						−7.09		−8.51			31.25
15			−7.32								96.25
NDHDA			−7.00
A.A			−6.63	−5.04	−4.37	−3.31		−6.72	−4.58	−4.97