Table 1.
Nanoparticles | Target | Dose | Result | References |
---|---|---|---|---|
Au | Mice (in vivo) | 2 × 105 PPB | Uptake of nanoparticles occurred in the small intestine | [157] |
Ag | Zebrafish (in vivo) | 5–100 μg/mL | Dose-dependent toxicity in embryos | [158] |
Ag, Cu, Al | Mice and Rat (in vivo) | 30–50 mg/kg | Blood-brain barrier penetration | [159] |
Ag, Mn | PC-12 cells (in vitro) | 1–100 μg/mL | Cell shrinkage and irregular membrane | [160] |
Ag, TiO2 | Murine macrophage cell line (in vitro) | 5 μg/mL | Aggregates of nanoparticles | [161] |
TiO2 | Mice (in vivo) | 5 g/kg | Show histopathological effects | [162] |
Cu, Mn | PC-12 cells (in vitro) | 10 μg/mL | Genes expression altered | [163] |
Al, Al2O3 | Rat (in vivo) | 25–250 μg/mL | Phagocytosis hindered | [164] |
Cu | Zebrafish (in vivo) | 0.25–1.5 mg/L | Biochemical, histopathological changes | [155] |