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. 2018 Jul 30;115(33):8430–8435. doi: 10.1073/pnas.1806614115

Fig. 3.

Fig. 3.

Proton sensitivity in vertebrate ASIC4. (A) Maximum-likelihood tree of ASIC4 amino acid sequences, rooted to zebrafish ASIC1.1. Bootstrap support (per 100) shown for selected branches. Example pH 4.0-gated currents for indicated ASICs shown on right. (Scale bars: x 10 s; y 0.1 µA.) “Δ24” constructs lack 24 N-terminal amino acids following the starting methionine. (B) Average (column) and individual (dots) pH 4.0-gated peak current amplitudes (color as in A). n = 10, except for uninjected, n = 25.