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Increased production of IL-6 and IL-1α by intestinal CX3CR1high Mϕs of Lyz2-cre; Spicflox/flox mice. (A–D) LPS-induced production of IL-6 (A), IL-1α (B), TNF-α (C), and IL-10 (D) by large intestinal CX3CR1high Mϕs and CX3CR1intermediate (int)/- cells. Mean values ± SEM from four independent experiments are shown. n.s., not significant. *P < 0.05.
