Fig. 1. MAO-N residues chosen for saturation mutagenesis marked in the homology model, which was built using the crystal structure of MAO-N-D3 (PDB: 2VVL). (A) Active site mutation sites (yellow), selected on the basis of induced fit docking of amine 1 (green). (B) Residues surrounding the substrate access tunnel (red) likewise chosen for mutagenesis (shown in green).
