Table 1.
EC50 values summarizing the relaxant effects of perillyl alcohol, carveol, and limonene on rat aortic rings. Values are expressed as means ± SEM.
| Contractile Agent | Perillyl Alcohol (µM) | Carveol (µM) | Limonene (µM) | |
|---|---|---|---|---|
| K+ | E+ | 277.7 ± 5.46 (6) | 662.1 ± 32.85 (7) a | 941.6 ± 28.02 (6) b |
| K+ | E− | 279.7 ± 22.01 (7) | 619.8 ± 37.15 (7) a | 1474.5 ± 27.08 (7) b,c |
| PHE | E+ | 443.3 ± 66.83 (6) d | 1333.3 ± 225.20 (10) a,e | 2159.1 ± 203.62 (7) b,f |
| PHE | E− | 433.3 ± 44.31 (7) d | 1237.34 ± 117.90 (9) a,e | 1216.7 ± 57.50 (7) c,f |
| BayK | E− | 221.4 ± 4.09 (5) | 598.2 ± 42.05 (5) a | 439.0 ± 31.76 (5) b,g |
E+, endothelium-intact aorta; E−, endothelium-denuded aorta; PHE, phenylephrine; a, p < 0.05, in compared to the corresponding POH value; b, p < 0.05, compared to the corresponding CV value; c, p < 0.05, endothelium-intact vs. endothelium-denuded; d, p < 0.05, compared to 277.7, 279.7, and 221.4 µM; e, p < 0.05 compared to 662.1, 619.8, and 598.2 µM; f, p < 0.05, compared to 941.6, 1474.5, and 439.0 µM; g, p < 0.05, BayK vs. limonene K+ E+ and K+ E−; Values are expressed as means ± SEM (n), n = number of experiments.