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Antiparasitic effect of thiophene derivative 5A. Viability of L. major-luc promastigotes incubated with 5A at 0.31 to 10 µM for 72 h. Evaluation of intraperitoneal mouse macrophages (IPΦ) cytotoxicity for 48 h, or monkey kidney cells (LLC-MK2) treated with 5A at concentrations of 0.31 to 40 µM for 72 h. Controls treated with 1% DMSO, or amphotericin B (amp B) at 5 µM.
