Table 3.
Effects of the ruthenium complex on HOMA2-IR index of pre-diabetic animals during treatment period. Values are presented as means (n = 6) in each group.
| Groups | Plasma Glucose (mmol/L) | Plasma Insulin (mIU/L) | HOMA-IR Values |
|---|---|---|---|
| NC | 4.60 ± 0.09 | 5.89 ± 0.90 | 1.20 ± 0.61 |
| Pre-D | 5.60 ± 0.32 * | 20.92 ± 3.45 * | 5.20 ± 2.98 * |
| MTF + HFHC | 6.60 ± 0.81 *,α | 18.00 ±3.12 * | 5.30 ± 1.02 * |
| MTF + DI | 4.30 ± 0.90 α | 7.57 ±1.32 *,α | 1.30 ±1.15 *,α |
| RU + HFHC | 5.60 ±1.02 *,α | 16.17± 1.88 *,α | 4.00 ±1.05 * |
| RU + DI | 4.70 ± 0.82 α | 8.29 ± 2.00 α | 1.70 ± 0.99 α |
*p < 0.05 by comparison with normal control (NC), α p < 0.05 by comparison with pre-diabetic control (Pre-D); Metformin and high fat high carbohydrate (MTF + HFHC); Metformin and diet intervention (MTF + DI); Ruthenium and high fat high carbohydrate (RU + MTF); and Ruthenium and diet intervention (RU + DI).