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. 2018 Jun 8;23(6):1396. doi: 10.3390/molecules23061396

Table 1.

Inhibitory activities of 9a–9n against PGAM1.

graphic file with name molecules-23-01396-i001.jpg

Entry Compounds R IC50 (μM) *
1 9a graphic file with name molecules-23-01396-i002.jpg >20 **
2 9b graphic file with name molecules-23-01396-i003.jpg >20
3 9c graphic file with name molecules-23-01396-i004.jpg >20
4 9d graphic file with name molecules-23-01396-i005.jpg >20
5 9e graphic file with name molecules-23-01396-i006.jpg >20
6 9f graphic file with name molecules-23-01396-i007.jpg 10.1 ± 0.5
7 9g graphic file with name molecules-23-01396-i008.jpg 13.2 ± 0.4
8 9h graphic file with name molecules-23-01396-i009.jpg 6.4 ± 0.4
9 9i graphic file with name molecules-23-01396-i010.jpg 10.2 ± 0.7
10 9j graphic file with name molecules-23-01396-i011.jpg >20
11 9k graphic file with name molecules-23-01396-i012.jpg 8.4 ± 2.7
12 9l graphic file with name molecules-23-01396-i013.jpg 5.9 ± 1.2
13 9m graphic file with name molecules-23-01396-i014.jpg 5.5 ± 1.1
14 9n graphic file with name molecules-23-01396-i015.jpg 6.0 ± 0.6
15 PGMI-004A 13 ± 0.1

* All IC50 values are reported as means ± SD from three determinations. ** The inhibition ratios at 20 μM were less than 50%.