Table 4.
Entry | Compounds | Structures | IC50 (μM) * |
---|---|---|---|
1 | 9h | 14.1 ± 1.9 | |
2 | 9k | 21.1 ± 1.7 | |
3 | 9l | 18.5 ± 2.3 | |
4 | 9m | 20.1 ± 1.4 | |
5 | 15b | 42.7 ± 3.9 | |
6 | 15d | 19.6 ± 2.2 | |
7 | 15f | 32.7 ± 0.9 | |
8 | 15h | 33.8 ± 6.1 | |
9 | 15i | 30.6 ± 2.4 | |
10 | 15j | 31.1 ± 4.5 | |
Gemcitabine | 0.193 | ||
PGMI-004A | 26.0 ± 2.1 |
* All IC50 values are reported as means ± SD from three determinations.