Figure 4.

Anti-obesity effects of loganic acid in ovariectomy (OVX)-induced obesity mice. (A,B) After 12 weeks of feeding, the total body weight and total fat percentage of the mice was measured in the sham-operated mice (Sham), the ovariectomized mice (OVX), and the OVX mice with oral administration of loganic acid (LA2, LA 10, and LA 50: 2, 10, and 50 mg/kg/day, respectively). The body weight and total fat of all of the mice were measured using an electronic scale and PIXImus small animal densitometer, respectively *: p < 0.05 vs. OVX mouse group (Tukey’s HSD post hoc test, ANOVA); (C) Hematoxylin and eosin (H&E)-stained images of liver and abdominal visceral fat tissues.