Table 4.
The concentrations of BA in different tissues on normal models after i.v. administrated BA and BA-LP (n = 5). Values are mean (SD).
| Time (min) | Concentration in Tissues (μg/g) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Heart | Liver | Spleen | Lung | Kidney | ||||||
| BA | BA-LP | BA | BA-LP | BA | BA-LP | BA | BA-LP | BA | BA-LP | |
| 15 | 0.34 (0.14) | 0.74 (0.39) | 1.06 (0.16) | 1.76 (0.18) | 0.36 (0.04) | 2.52 (1.90) | 1.09 (0.20) | 2.36 (0.47) | 15.01 (1.44) | 6.51 (1.29) |
| 30 | 1.29 (0.78) | 1.95 (0.32) | 3.18 (0.34) | 8.75 (2.18) | 0.32 (0.04) | 3.71 (1.04) | 0.96 (0.20) | 1.50 (0.54) | 6.72 (1.71) | 7.10 (2.18) |
| 60 | 0.36 (0.10) | 4.07 (0.45) | 0.48 (0.16) | 7.53 (1.93) | 0.15 (0.02) | 8.84 (2.59) | 0.41 (0.09) | 2.92 (0.54) | 2.52 (0.44) | 6.77 (1.62) |
| 90 | 0.20 (0.08) | 4.44 (0.81) | 0.27 (0.18) | 2.21 (0.86) | 0.06 (0.01) | 1.44 (0.78) | 0.23 (0.03) | 0.76 (0.18) | 1.84 (0.32) | 6.49 (0.65) |
| 120 | 0.10 (0.02) | 0.68 (0.34) | 0.06 (0.01) | 0.99 (0.31) | 0.02 (0.004) | 0.93 (0.33) | 0.12 (0.02) | 0.36 (0.17) | 1.25 (0.20) | 2.21 (0.50) |
| 240 | ND | 0.43 (0.06) | ND | 1.05 (0.30) | ND | 0.20 (0.06) | ND | 0.18 (0.05) | ND | 0.94 (0.12) |
| 360 | ND | 0.11 (0.04) | ND | 0.35 (0.18) | ND | 0.11 (0.16) | ND | 0.16 (0.10) | ND | 0.74 (0.15) |
The tissue samples were obtained with five rats at each time point. ND means not detected.