Table 5.

Clinical data in patients treated with rosuvastatin and metformin.

Patient Sex/Age (years)	Time Post Dose (h)	Drug/Dose Peros (mg)	C (ng mL−1) Mean ± S.D.(n = 3)	Co-Administered Drugs
♀/57	21/2	Metformin/1000 × 1 × 30 days Rosuvastatin/10 × 1 × 30 days	1956 ± 93 22.2 ± 0.4	Acetylsalicylic acid 100 mg tb 1 × 1
♂/64	11	Rosuvastatin/20 × 1 × 30 days	16.2 ± 1.4	Furosemide 40 mg tb 1 × 1, ramipril 2.5 mg tb 1 × 1, carvedilol 6.35 mg tb 1 × 1.
♂/63	16	Rosuvastatin/20 × 1 × 30 days	9.21 ± 0.39	Nadroparin 5700 anti-ha 1 × 1 subcutaneous, omeprazole caps 20 mg 1 × 1, metoprolol tb 25 mg 1 × 2, sulbactam 1 g & ampicillin i.v. 1 × 3 × 5 days, acetyl salicylic acid 100 mg E.C.tb 1 × 1, atalopram 20 mg 1 × 1.
♀/80	21/2	Metformin/1000 × 1 × 30 days	2635 ± 67	Acetylsalicylic acid 100 mg tb 1 × 1, insuline glarine 100 iu/mL 10IU ×1 night subcutaneous, Ramipril 5 mg tb 1 × 1, nadropanin 2850 Anti-xa 1 × 1, piracetam i.v. 1 × 2.
♀/83	10	Metformin/1000 × 2 × 30 days	1850 ± 55	Furosemide 20 mg tb 1 × 1, 1 × 1, insuline glarine 100 iu/mL 14IU ×1 night subcutaneous, pantoprazole 40 mg caps 1 × 1, T4-50 1 × 1, carvedilol 12.5 mg tb 1 × 2, apixaban 2.5 mg tb 1 × 2, Lutein/Zeaxanthine/Mesozeaxanthine caps 1 × 1, VITAMIN D3 2000 IU 1 × 1.
♂/70	21/2	Metformin/850 × 2 × 30 days	1856 ± 84	Ezetimibe/simvastatin 10/40 mg tb 1 × 1, gliclazide 30 mg tb 1 × 1, sertraline 50 mg tb 1 × 2, galantamine 8 mg caps 1 × 1, levodopa/carvidopa/entacapone 100/25/200 tb 1 × 3, clopidogrel 75 mg tb 1 × 1.
♀/88	12	Metformin/850 × 1 × 30 days	1676 ± 60	Atorvastatin tb 40 mg 1 × 1, furosemide 20 mg i.v. 2 × 3, bisoprostol 10 mg 1 × 1, insuline glarine 100 iu/mL 10IU ×1 night subcutaneous, thyrormone 100 mg 1 × 1, acetyl salicylic acid 100 mg E.C.tb 1 × 1, digoxin tb 0.25 mg ½ × 1.
♀/88	16	Metformin/850 × 1 × 30 days	226 ± 12	Atorvastatin tb 40 mg 1 × 1, furosemide 20 mg i.v. 2 × 3, insuline glarine 100 iu/mL 10IU ×1 night subcutaneous, thyrormone 100 mg 1 × 1, digoxin tb 0.25 mg ½ × 1, acetyl salicylic acid 100 mg E.C. tb 1 × 1.