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Hepatic mRNA expression of SREBP-1c (A); ACC (B); PPAR-α (C) and CPT-1a (D) in ALD rats. N: normal group, M: model group, P: silybin positive group, G1: 18α-GA:18β-GA = 10:0, G2: 18α-GA:18β-GA = 8:2, G3: 18α-GA:18β-GA = 6:4, G4: 18α-GA:18β-GA = 5:5, G5: 18α-GA:18β-GA = 4:6, G6: 18α-GA:18β-GA = 2:8, G7: 18α-GA:18β-GA = 0:10. The values were expressed as mean ± SD. ** p < 0.01 vs. normal group, # p < 0.05, ## p < 0.01 vs. model group.
