Fig. 1.

Identification of patients requiring renal replacement therapy (RRT) upon sepsis diagnosis and over the first week of ICU treatment. Logistic regression and AUROC analysis for the requirement of RRT in all patients at baseline (a) and during the first 7 days of ICU therapy in patients with no prior RRT (b). Multivariate Cox regression analysis was corrected for age and the presence of comorbidities. AUROC area under the receiver operating characteristic curve, CI confidence interval, CRP C-reactive protein, IQR interquartile range, LR likelihood ratio, MR-proADM mid-regional proadrenomedullin, N number, OR odds ratio, PCT procalcitonin, RRT renal replacement therapy