Table 1.
Characteristics of participants with versus without PAD.
| With PAD (n=34) | Without PAD (n=l0)a | p-value | |
|---|---|---|---|
| Age, years, mean (SD) | 73.54 (6.40) | 73.07 (4.68) | 0.83 |
| Male sex, n (%) | 24 (70.59) | 3 (30.00) | 0.030 |
| African American race, n (%) | l9 (55.88) | 5 (50.00) | l.00 |
| Current smoker, n (%) | 9 (26.47) | 0 (0) | 0.l7 |
| Former smoker, n (%) | l9 (55.88) | 6 (66.67) | 0.7l |
| Ankle-brachial index, mean (SD) | 0.67 (0.15) | l.l4 (0.07) | <0.000l |
| Body mass index, kg/m2, mean (SD) | 29.58 (4.01) | 27.59 (5.06) | 0.22 |
| Diabetes, n (%) | 15 (44.12) | 1 (11.11) | 0.l2 |
| Myocardial infarction, n (%) | l (2.94) | 0 (0.00) | l.00 |
| Angina, n (%) | 4 (11.76) | 1 (ll.ll) | l.00 |
| Pulmonary disease, n (%) | 6 (17.65) | 1 (ll.ll) | l.00 |
| Cancer, n (%) | ll (32.35) | 2 (22.22) | 0.70 |
| History of revascularization, n (%) | ll (32.35) | 0 (0) | 0.046 |
| Six-minute walk distance, feet, mean (SD) | 1190.6 (223.4) | l387.3 (488.3) | 0.08 |
| Usual paced 4-meter walking velocity, m/s, mean (SD) | 0.81 (0.14) | 0.92 (0.25) | 0.08 |
| Fast paced 4-meter walking velocity, m/s, mean (SD) | l.l2 (0.22) | l.l6 (0.26) | 0.68 |
| MtDNA copy number, arbitrary units, mean (SD)b | 766 (312) | 626 (269) | 0.2l |
BMI, body mass index; MtDNA, mitochondrial DNA; PAD, peripheral artery disease
a
One person without PAD had missing data for smoking, BMI, comorbidities, and functional performance measurements.
b
Mitochondrial DNA copy number is measured relative to nuclear DNA and is expressed as arbitrary units.