. Author manuscript; available in PMC: 2018 Dec 1.

Published in final edited form as: J Cardiovasc Med (Hagerstown). 2017 Dec;18(12):954–961. doi: 10.2459/JCM.0000000000000549

Table 2.

Unadjusted and adjusted associations between osteoprotegerin and indicators of aortic stiffness

		Unadjusted		Model 1		Model 2

Outcome	Median (25th, 75th ranges)	Coefficient^a (95% CI)	P value	Coefficient^a (95% CI)	P value	Coefficient^a (95% CI)	P value
SAC (ml/mmHg)	1.35 (1.07, 1.65)	−0.119 (−0.144, −0.094)	<0.001	−0.064 (−0.086, −0.041)	<0.001	−0.061 (0.086,0.036)	<0.001
Ea (mmHg/ml)	1.62 (1.41, 1.86)	0.056 (0.034, 0.078)	<0.001	0.032 (0.011,0.054)	0.003	0.037 (0.014, 0.059)	0.001

All models account for correlation among family members; Model 1, adjusted for age and sex; Model 2, adjusted for age, sex, history of hypertension, diabetes, coronary heart disease, current smoking status, and estimated glomerular filtration rate; CI, confidence interval; Ea, effective arterial elastance; OPG, osteoprotegerin; SAC, systemic arterial compliance.

Represents a one SD change in OPG and the unit change in the corresponding outcome.