Figure 1.

(A) All-cause mortality among primary prevention trials. (B) Sudden cardiac death among primary prevention trials. For each randomized trial, the point estimates of the hazard ratio for individual studies are represented by circle with 95% confidence intervals shown as bars. AMIOVIRT, Amiodarone vs. Implantable Defibrillator Randomized Trial; CI, confidence interval; CAT, Cardiomyopathy Trial; COMPANION, Comparison of Medical Therapy, Pacing, and Defibrillation in Heart Failure trial; DANISH, Danish Study to Assess the Efficacy of ICDs in Patients with Non-Ischaemic Systolic Heart Failure on Mortality; DEFINITE, Defibrillators in Non-Ischaemic Cardiomyopathy Treatment Evaluation; HR, hazard ratio; ICD, implantable cardioverter-defibrillator; MT, medical therapy; SCD-HeFT, Sudden Cardiac Death in Heart Failure Trial.