Table 1.
Ratios of WT α-synuclein and chimeras obtained from mature fibrils taken from the endpoint of the co-incubated ThT assays, as determined by ESI-MS analysis of the dissolved fibrils.
pH 7.3 | pH 5.8 | |
---|---|---|
αS : AAA | - | - |
αS : BAA | 1 : 3.4 | 1 : 3.4 |
αS : AAB | 1 : 2.4 | 1 : 4.8 |
αS : BAB | 1 : 1.5 | 1 : 1.5 |
αS : ABA | 3.4 : 1 | 1 : 1 |
αS : BBA | 1 : 1 | 1 : 5 |
αS : ABB | 4 : 1 | 3.5 : 1 |
αS : BBB | 4 : 1 | 1.2 : 1 |
αS : βΕ61Α | 1.6 : 1 | - |