Table 2.
Demographic and Clinical Characteristics of Study Participants at the Time of Quality of Life Assessment at Virologic Failure
| Characteristic | Total (N=512) |
|---|---|
| Sex | |
| Male | 252 (49%) |
| Female | 260 (51%) |
| Age | |
| Median (IQR) | 39 (34; 44) |
| 18–29 | 51 (10%) |
| 30–39 | 227 (44%) |
| 40–49 | 178 (35%) |
| 50+ | 56 (11%) |
| Race/Ethnicity | |
| Black | 330 (64%) |
| Non-black | 182 (36%) |
| Country | |
| Brazil | 12 (2%) |
| India | 158 (31%) |
| Kenya | 48 (9%) |
| Malawi | 111 (22%) |
| Peru | 9 (2%) |
| South Africa | 103 (20%) |
| Tanzania | 17 (3%) |
| Thailand | 7 (1%) |
| Zimbabwe | 47 (9%) |
| BMI (kg/m2) | |
| Median (IQR) | 22 (19; 26) |
| Underweight (<18) | 55 (11%) |
| Normal (18–24) | 295 (58%) |
| Overweight (25–29) | 110 (21%) |
| Obese (≥30) | 52 (10%) |
| VL (HIV-1 RNA copies/mL) | n=510 |
| Median (IQR) | 33,360 (8,033; 138,153) |
| <10,000 | 145 (29%) |
| 10,000–100,000 | 206 (40%) |
| >100,000 | 159 (31%) |
| CD4 (cell counts/mm³) | n=507 |
| Median (IQR) | 135 (53; 271) |
| <50 | 122 (24%) |
| 50–199 | 194 (38%) |
| 200–349 | 121 (24%) |
| ≥350 | 70 (14%) |
| History of AIDS | |
| Yes | 150 (29%) |
| No | 362 (71%) |
| Number of comorbidities | |
| 0 | 180 (35%) |
| 1 | 148 (29%) |
| 2 | 80 (16%) |
| ≥3 | 104 (20%) |
| Time on 1st-line ART (years) | |
| Median (IQR) | 4.2 (2.3; 6.2) |
| <4 | 245 (48%) |
| 4-<7 | 177 (34%) |
| ≥7 | 90 (18%) |