Table 4.
Adjusted difference in mean QoL score by VL, CD4, BMI, history of AIDS and number of comorbidities (95% Confidence Interval). All differences are adjusted for the other variables shown and also for country.
| Parameter | General Health Perceptions (GHP) | Physical Functioning (PF) | Role Functioning (RF) | Social Functioning (SF) | Cognitive Functioning (CF) | Pain (P) | Mental Health (MH) | Energy / Fatigue (E/F) |
|---|---|---|---|---|---|---|---|---|
| VL (copies/ml) >100K vs. ≤100K |
−7.9(−11.5; −4.4) p<.001 |
−4.4(−7.7; −1.1) p=0.010 |
−6.5(−11.5; −1.5) p=0.011 |
−2.1(−5.1; 0.8) p=0.158 |
−2.7(−5.7; 0.3) p=0.080 |
−4.3(−8.4; −0.2) p=0.037 |
−2.9(−5.8; −0.0) p=0.047 |
−5.1(−8.8; −1.5) p=0.006 |
| CD4 (cells/mm3) <50 vs. ≥50 |
−9.4(−13.3; −5.4) p<.001 | −4.3(−8.0; −0.6) p=0.023 |
−3.9(−9.3; 1.6) p=0.163 |
−6.6(−9.9; −3.4) p<.001 |
−2.7(−6.1; 0.6) p=0.111 |
−4.9(−9.4; −0.4) p=0.033 |
−5.7(−8.9; −2.5) p=0.001 |
−5.6(−9.7; −1.5) p=0.007 |
| BMI (kg/m2) <18 vs. ≥18 |
* | −6.8(−11.6; −1.9) p=0.006 |
* | −5.7(−9.9; −1.4) p=0.009 |
* | * | * | * |
| History of AIDS Yes vs. No |
* | −4.7(−8.0; −1.4) p=0.005 |
* | * | * | * | *- | −6.0(−9.6; −2.4) p=0.001 |
| Number of comorbidities ≥3 vs. <3 |
* | * | −7.2(−13.1; −1.3) p=0.016 |
* | * | −9.7(−14.5; −4.9) p<.001 |
* | * |
*
Not included in the multivariable model chosen by backwards variable selection (see Methods).