Table 1.

Results of Multivariable Cox Proportional Hazards Model on Overall Survival

		95% Confidence Interval
Variables	Hazard Ratio	Lower	Upper	p
Breast Cancer (METABRIC)
TRPA1 expression
Low (below median)	reference	reference	reference	reference
High (above/including median)	1.17	1.02	1.34	0.021
Primary receptor status
ER+/HER2−	reference	reference	reference	reference
HER2+	1.37	1.16	1.61	1.75 × 10−4
Triple-negative	1.07	0.89	1.29	0.497
Primary stage at diagnosis
Stage I	reference	reference	reference	reference
Stage II	1.25	1.06	1.48	0.008
Stage III	2.82	2.12	3.76	1.22 × 10−12
Stage IV	6.43	3.17	13.04	2.48 × 10−7
Grade at diagnosis
Grade 1	reference	reference	reference	reference
Grade 2	1.26	0.94	1.69	0.124
Grade 3	1.61	1.20	2.15	1.45 × 10−3
Lung Cancer (TCGA)
TRPA1 expression
Low (below median)	reference	reference	reference	reference
High (above/including median)	1.34	1.02	1.77	0.039
Gender
Female	reference	reference	reference	reference
Male	1.10	0.85	1.41	0.47
Tobacco use
Never smoker	reference	reference	reference	reference
Former smoker, quit >15 years	0.77	0.47	1.27	0.31
Former smoker, quit <15 years	0.72	0.45	1.14	0.16
Current smoker	0.79	0.49	1.29	0.35
Age at diagnosis
Under 50 years	Ref	Ref	Ref	Ref
50 to 59 years	1.09	0.59	2.04	0.78
60 to 69 years	1.07	0.59	1.92	0.83
Over/including 70 years	1.47	0.81	2.64	0.20
Stage at diagnosis
Stage I	reference	reference	reference	reference
Stage II	1.59	1.20	2.10	1.14 × 10−3
Stage III	2.46	1.84	3.27	8.19 × 10−10
Stage IV	2.65	1.53	4.59	5.10 × 10−4
Histology
Adenocarcinoma	reference	reference	reference	reference
Squamous	0.97	0.74	1.28	0.84