Table 1.

Probability of treatment discontinuation and relapse at 6 months

	Mean	SEa	Source
Probability of treatment discontinuation at 6 months due to relapse
Brexpiprazole	16.0%	0.8%	Fleischhacker et al17
Lurasidone	30.9%	1.5%	Tandon et al21
Cariprazine	18.5%	0.9%	Durgam et al20
Probability of treatment discontinuation at 6 months due to AEs
Brexpiprazole	23.3%	1.2%	Fleischhacker et al17
Lurasidone	7.8%	0.4%	Tandon et al21
Cariprazine	8.2%	0.4%	Durgam et al20
Probability of treatment discontinuation at 6 months due to other reasonsb
Brexpiprazole	16.5%	0.8%	Fleischhacker et al17
Lurasidone	32.0%	1.6%	Tandon et al21
Cariprazine	18.8%	0.9%	Durgam et al20
Probability of relapse in composite arm
Composite therapy	14.9%b	NA	Calculation
Olanzapine	4.0%	0.2%	Beasley et al43
Risperidone	15.0%	0.8%	Csernansky et al39
Quetiapine	15.4%	0.8%	Peuskens et al44
Ziprasidone	16.3%	0.8%	Arato et al45
Aripiprazole	23.7%	1.2%	Pigott et al46

Notes:

^aAll SEs assumed to be 5% of the mean;

^bother reasons included cost of medication, nonadherence, patient preference, or unknown.

Abbreviation: NA, not applicable.