Fig. 2.

Collecting k-mers from annotated exons in the reference genome. These k-mers are stored in a table that will be used to compare with the reads. a Annotations from one chromosome. Green bars stand for valid exons while gray bars stand for the invalid ones which do not contain any circular splicing signal. b Extracting K-mer. Yellow arrows stand for the k-mers from the boundary (red frame) of each exon. All of k-mers from short exon will be considered (the second case). “S” or “E” is the value of part tag. c Showing all annotation positions of the k-mer with purple box in B. Green box: all information kept for one annotation position