Table 1.

Overview of six reported articles of vulvovaginitis due to Cryptococcus species (1985- 2018)

NO	Age/year	Location	No. Total/ case samples	Agent	Clinical presentation	Examination	Treatment	Case characteristics	Reference
1	NI/ 1985	USA	805/1	Cryptococcus. ungulaticus	Vulvovaginal complaints	Culture	NI	NI	[16]
2	60/1987	USA	Case report	Cryptococcus. neoformans	Cutaneous lesion	Culture and Biopsy	NI	Renal transplant recipient	[17]
3	72/1993	NI	Case report	Cryptococcus. spp	Colon cancer	Culture	FLC	Colon cancer	[18]
4	20/2005	Malaysia	Case report	Cryptococcus. neoformans	Vulvovaginal complaints	Biopsy	Oral FLC	NI	[19]
5	NI/2009	Saudi Arabia	1000/1	Cryptococcus. neoformans	NI	Culture and API20C kit	NI	NI	[20]
6	23/2018	Iran	Case report	Cryptococcus. magnus	severe itching and vaginal irritation	Culture and sequencing	KCZ	immunocompetent	Current case

NI =Not indicated; spp,, species; FLU, fluconazole; ketoconazole, KCZ