Table 3. Cognitive performance in the LRRK2 G2019S and GBA mutation carrier groups.

Cognitive Domain	Measure	Asymptomatic LRRK2 mutation carriers (N = 88)	Asymptomatic GBA mutation carriers (N = 38)	p-value* for test of difference between LRRK2 and GBA groups only
Global cognition	MoCA
	Mean (SD; range)	26.5 (2.72; 19–30)	27.6 (1.86; 20–30)	0.0427
	Number with Missing Data N (%)	2 (2)	1 (3)
Verbal memory	HVLT Immediate Recall
	Mean (SD; range)	24.6 (6.03; 5–34)	27.5 (5.05; 14–35)	0.0181
	Number with Missing Data N (%)	2 (2)	2 (5)
	HVLT Delayed Recall
	Mean (SD; range)	8.8 (2.96; 0–12)	9.7 (2.27; 4–12)	0.1216
	Number with Missing Data N (%)	2 (2)	2 (5)
	HVLT Delayed Recognition
	Mean (SD; range)	11.1 (1.89; 0–12)	11.5 (0.93; 8–12)	0.3895
	Number with Missing Data N (%)	3 (3)	4 (11)
Visuospatial function	Benton Judgment of Line Orientation
	Mean (SD; range)	12.7 (2.08; 5–15)	12.9 (1.90; 8–15)	0.2660
	Number with Missing Data N (%)	2 (2)	2 (5)
Processing speed/attention	Symbol Digit Modalities Test
	Mean (SD; range)	44.2 (11.7; 0–74)	47.0 (8.49; 29–68)	0.3235
	Number with Missing Data N (%)	3 (3)	4 (11)
Executive function/working memory	Letter-Number Sequencing
	Mean (SD; range)	10.7 (3.14; 2–20)	10.9 (2.63; 6–18)	0.7698
	Number with Missing Data N (%)	2 (2)	2 (5)
	Semantic Fluency total
	Mean (SD; range)	54.0 (14.6; 18–98)	54.1 (11.5; 25–78)	0.7457
	Number with Missing Data N (%)	2 (2)	2 (5)

*Analyses are adjusted for age, sex, education and GDS-15 score