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. 2018 Aug 20;13(8):e0202604. doi: 10.1371/journal.pone.0202604

Table 2. Use of antihypertensive medications.

  Patients with hypertension (%) Uncontrolled Controlled
Antihypertensive Medication  
    Yes 4858 (97.4) 2402 (95.0) 2456 (100.0)
    No 127 (2.6) 127 (5.0) 0 (0.0)
Antihypertensive medication sorted by substance class
RAS inhibitors (total) 4134 (82.9) 2026 (80.1) 2108 (85.9)
    ACE inhibitors 2439 (48.9) 1140 (45.1) 1299 (52.9)
    Angiotensin receptor blocker 2011 (40.3) 1031 (40.8) 980 (39.9)
    Renin inhibitors 285 (5.7) 176 (6.9) 109 (4.4)
Combined RAS blockade (total) 585 (11.7) 313 (12.4) 272 (11.1)
    ACEI and ARB 396 (7.9) 197 (7.8) 199 (8.1)
    ACEI and renin inhibitor 84 (1.7) 48 (1.9) 36 (1.5)
    ARB and renin inhibitor 105 (2.1) 68 (2.7) 37 (1.5)
    ACEI, ARB and renin inhibitor 16 (0.3) 8 (0.3) 8 (0.3)
Beta blocker 2844 (57.1) 1474 (58.3) 1370 (55.8)
Vasodilator 219 (4.4) 114 (4.5) 105 (4.3)
Ca channel blocker 1951 (39.1) 1088 (43.0) 863 (35.1)
Central Antiadrenergic 627 (12.6) 403 (15.9) 224 (9.1)
Peripheral Antiadrenergic 327 (6.6) 215 (8.5) 112 (4.6)
Diuretics (total) 3119 (62.6) 1546 (61.1) 1573 (64.1)
    Loop diuretic 1988 (39.9) 966 (38.2) 1022 (41.6)
    Thiazides and analogs 1564 (31.4) 803 (31.8) 761 (30.1)
    Potassium-sparing diuretics 501 (10.1) 200 (7.9) 301 (12.3)

Usage of a given drug class in percent was calculated in relation to all hypertensive patients, all hypertensive patients with uncontrolled blood pressure (≥140/90 mmHg), and all hypertensive patients with controlled blood pressure (<140/90 mmHg), respectively. RAS, renin-angiotensin system. ACEI, angiotensin converting enzyme inhibitors. ARB, angiotensin receptor blockers. RI, renin inhibitor. Ca, Calcium.