Table 1.
Characteristics of 1658 ART-Naïve Patients in Central NC at First Genotype Sequencing During the Study Period, 1997–2014
| Characteristic | No. (%) |
|---|---|
| Sex | |
| Male | 1211 (73) |
| Female | 447 (27) |
| Race/ethnicity | |
| Black | 1024 (62) |
| White | 454 (27) |
| Other race or Hispanic/Latino | 180 (11) |
| Age, y | |
| <20 | 56 (3) |
| 20–29 | 473 (29) |
| 30–39 | 456 (28) |
| 40–49 | 439 (26) |
| ≥50 | 234 (14) |
| HIV transmission risk factora | |
| MSM | 763 (50) |
| IDU | 69 (7) |
| MSM + IDU | 16 (2) |
| HIV-1 subtype B | 1620 (98) |
| CD4 cell count, cells/mm3 | |
| <200 | 544 (40) |
| 200–349 | 272 (20) |
| 350–499 | 264 (19) |
| ≥500 | 295 (21) |
| Median CD4 (IQR) | 283 (75–465) |
| No CD4 within 90 d of sequencing | 283 |
| Viral load, copies/mL | |
| Median viral load | 64 381 |
| Median log10 viral load (IQR) | 4.8 (4.2–5.3) |
| No viral load within 90 d of sequencing | 280 |
| Transmission cluster | |
| Sequence identified in cluster | 1084 (65) |
| Sequence not in cluster | 574 (35) |
Abbreviations: ART, antiretroviral therapy; IDU, injection drug user; IQR, interquartile range; MSM, men who have sex with men.
aFor MSM, there were 135 missing values, and the percentage is based on the number of patients with nonmissing data (n = 1523). For IDU, data were only available for UNC clinical cohort patients, and the percentage is based on the number of UNC patients with nonmissing data (n = 975). The percentage for MSM + IDU is based on the total number of UNC patients with nonmissing data on both MSM and IDU (n = 956).