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. 2018 Jul 4;44(5):958–965. doi: 10.1093/schbul/sby096

Table 3.

Summary of the Findings Involving Hippocampal Neurogenesis in Rodent Models of Cacna1c/Cav1.2 Dysfunction

Model Proliferation Rate Immature Neurons Cell Survival Dentate Gyrus Size
Lee et al51 Forebrain-Cav1.2 CkO (−/−) n.d. n.d.
Temme et al50 Neuron-specific deletion of Cav1.2 CkO (−/−) n.d.
Völkening et al68 TgGLAST-CreERT2 /Cacna1cfl/fl /RCE:loxP mice (Mouse model with Cacna1c-deficient Type-1 cells)
Moon et al, this study Cacna1c+/− rat model n.d. n.d.

Note: n.d., no significant difference seen.