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. Author manuscript; available in PMC: 2019 Apr 1.
Published in final edited form as: Arthritis Rheumatol. 2018 Mar 7;70(4):555–565. doi: 10.1002/art.40405

Figure 6. Microbial dysbiosis in Lewis and Fischer rats.

Figure 6

A, PCA of species level data from samples taken from the sites indicated. Each data point represents the first three principal components from the analysis of a single sample from one animal. The distribution of samples from Lewis (sphere) and Fischer (tetrahedron) backgrounds are represented by ellipsoids (brown and blue, respectively), with HLA-B27 and wild-type genotypes indicated by red and green, respectively. B, Overlap between HLA-B27-induced dysbiosis on Lewis and Fischer backgrounds. Microbes with increased (red) or decreased (black) relative frequencies in HLA-B27 transgenic rats compared to wild-type are listed. All microbes shown are differentially represented in HLA-B27 Lewis and Fischer rats (p <0.05, q<0.1).