Table 2.
Number of patients requiring additional medication
| Group N (n=15) | Group H (n=15) | p | |
|---|---|---|---|
| 4 minutes after induction | 0 | 4 | 0.100 |
| 3 minutes after intubation | 1 | 3 | 0.598 |
| 3 minutes after skin incision | 0 | 1 | 1 |
| 3 minutes after sternotomy | 0 | 3 | 0.224 |
| LIMA period | 0 | 1 | 1 |
| After heparinisation | 0 | 0 | |
| During anastomosis | 0 + | 11 | 0.000 |
| During haemostasis | 0 | 0 | |
| During sternum closure | 0 | 0 | |
| At the end of the operation | 0 | 0 |
+
p<0.001: When the two groups were compared (according to the Bonferroni correction, p<0.004 was considered as statistically significant).
In Group N, the ephedrine application in 1 patient at T3 was required due to hypotension; the ephedrine application in 1 patient in Group H during anastomosis was required due to hypotension induced by surgical manipulation. Other additionally required drugs were remifentanil (0.1 μg kg−1 IV push) due to hypertension. LIMA: Left internal mammary artery