Figure 3.
(a) Representative protein DESI-MS spectra of normal and HGSC ovarian tumor with optimized FAIMS parameters. Mass spectra are averages of 10 scans. Different charge states of the same protein species are denoted by same colored labels. (b) Zoomed in mass spectra of normal and HGSC samples, highlighting the observance of m/z 1442.339, identified as S100A6, within the cancer tissue. (c) DESI-MS ion images obtained from normal, pure cancer, and mixed normal/cancer ovarian tissue sections. Ion images are in the same scale. H&E stained images are of a serial ovarian tissue sections as protein conditions are not histologically compatible.