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. 2018 Aug 14;9:1877. doi: 10.3389/fmicb.2018.01877

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Copyright © 2018 Imbert, Meyer, Palous, Brossas, Uzunov, Touafek, Gay, Trosini-Desert and Fekkar.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Aspergillus PCR performed in BAL is highly predictive of 90-day mortality in invasive pulmonary aspergillosis. (A) Patients with initial fungal loads below 500 copies/mL (n = 13; 76.9% survival) have more favorable outcomes than other patients (n = 19; 31.6% survival): p < 0.05 by Log-rank (Mantel-Cox) test; hazard ratio 0.23 (95% CI of ratio 0.08–0.65). (B) Patients with initial GM indices below 1.5 (n = 15; 80% survival) have more favorable outcomes than other patients (n = 15; 20% survival): p < 0.005 by Log-rank (Mantel-Cox) test; hazard ratio 0.16 (95% CI of ratio 0.05–0.47).