Table 1.
Diameter of the Inhibition Zone (DIZ) of the title compounds 5a–l, AMP, and FLC against Gram-positive bacteria, Gram-negative bacteria, and fungi.
| Compound No. | DIZ in mm ± S.D.* | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Strain | ||||||||||||
| Gram-Positive Bacteria | Gram-Negative Bacteria | Fungi | ||||||||||
|
B. Subtilis |
E. Fecalis |
MRSA |
S. Aureus |
E. Coli |
K. Pneumonia |
P. Vulgaris |
Ps. Aeruginosa |
S. Enteridis |
A. Niger |
C. Albicans |
P. Notatum |
|
| 5a | 9 ± 0.0 | 9 ± 1.0 | 9 ± 0.0 | 19 ± 0.0 | 13 ± 0.9 | −ve | −ve | 13 ± 0.4 | 9 ± 0.0 | 8 ± 0.0 | 11 ± 0.4 | 15 ± 0.1 |
| 5b | 15 ± 1.0 | 9 ± 0.0 | −ve | 19 ± 0.0 | 19 ± 1.1 | 11 ± 0.6 | −ve | 14 ± 0.3 | 9 ± 0.0 | 8 ± 0.0 | 10 ± 0.3 | 15 ± 0.7 |
| 5c | 15 ± 0.8 | 9 ± 0.0 | 11 ± 0.4 | 21 ± 0.7 | 13 ± 0.3 | −ve | −ve | 9 ± 0.0 | 9 ± 0.0 | 17 ± 0.4 | 8 ± 0.0 | 18 ± 0.3 |
| 5d | 16 ± 0.2 | 18 ± 1.3 | 11 ± 0.0 | 14 ± 0.3 | 14 ± 0.8 | 11 ± 0.3 | −ve | 11 ± 0.3 | 9 ± 0.0 | 8 ± 0.0 | 14 ± 0.2 | 8 ± 0.0 |
| 5e | 11 ± 0.8 | 11 ± 0.0 | −ve | −ve | 13 ± 0.44 | −ve | −ve | 9 ± 0.2 | 9 ± 0.0 | 15 ± 0.7 | 14 ± 1.1 | 9 ± 0.5 |
| 5f | 9 ± 0.0 | 11 ± 0.6 | 13 ± 1.6 | 16 ± 0.5 | 14 ± 0.0 | −ve | −ve | 18 ± 0.5 | 15 ± 0.7 | 8 ± 0.0 | 18 ± 0.0 | 15 ± 1.6 |
| 5g | 9 ± 0.4 | 9 ± 0.5 | 11 ± 0.0 | 14 ± 0.4 | 15 ± 1.0 | −ve | −ve | 9 ± 0.0 | 9 ± 0.0 | 17 ± 0.1 | 18 ± 0.0 | 14 ± 1.0 |
| 5h | 22 ± 1.6 | 14 ± 0.3 | 11 ± 0.5 | 14 ± 0.4 | 14 ± 0.3 | −ve | 11 ± 0.7 | 11 ± 0.6 | 9 ± 0.0 | 11 ± 0.1 | 25 ± 1.6 | 16 ± 0.5 |
| 5i | 13 ± 0.6 | 12 ± 0.9 | −ve | 19 ± 0.0 | 17 ± 0.6 | −ve | −ve | 14 ± 0.5 | 16 ± 0.2 | 8 ± 0.0 | 11 ± 0.2 | 18 ± 1.2 |
| 5j | 12 ± 0.6 | 11 ± 0.2 | −ve | 9 ± 0.2 | 13 ± 0.2 | −ve | 11 ± 0.2 | 9 ± 0.7 | 9 ± 0.0 | 16 ± 0.5 | 13 ± 0.3 | 14 ± 0.5 |
| 5k | 14 ± 0.4 | 11 ± 0.5 | −ve | 9 ± 0.0 | 14 ± 0.0 | −ve | −ve | 9 ± 0.6 | 9 ± 0.1 | 8 ± 0.0 | 13 ± 1.0 | 16 ± 0.4 |
| 5l | 15 ± 0.4 | 9 ± 0.8 | −ve | 9 ± 0.0 | 14 ± 0.0 | −ve | −ve | 12 ± 0.8 | 9 ± 0.0 | 8 ± 0.0 | 15 ± 0.7 | 14 ± 0.5 |
| AMP | 30 ± 0.0 | −ve | 36 ± 0.7 | −ve | 45 ± 1.0 | 32 ± 0.4 | 18 ± 0.4 | 35 ± 1.0 | 30 ± 0.5 | ND | ND | ND |
| FLC | ND | ND | ND | ND | ND | ND | ND | ND | ND | 21 ± 0.5 | 16 ± 0.8 | 15 ± 0.0 |