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. 2018 Jul 23;18(3):3185–3192. doi: 10.3892/mmr.2018.9305

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Copyright: © Liu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — Suppression of the transcription factor activity of p53 and c-Jun with GK treatment in OGD-induced SH-SY5Y cells. (A) Western blot analysis of the protein expression levels of p-p53, p53, p-c-Jun and c-Jun in SH-SY5Y cells with different concentrations of GK treatment (12.5, 25 and 50 µg/ml) and reoxygenation for 1 h. (B) Quantity one software was used for quantitative analysis of p-p53/p53 and p-c-Jun/c-Jun. The results present averages of three independent experiments (mean ± SD). ^#P<0.05 vs. control group, **P<0.01 and ***P<0.001 vs. OGD group. GK, ginkgolide K; OGD, oxygen-glucose deprivation.