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. 2018 Jul 23;18(3):3185–3192. doi: 10.3892/mmr.2018.9305

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Copyright: © Liu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 6. — Suppression of Bax/Bcl-2 ratio and cascade protein activities with GK treatment in OGD-induced SH-SY5Y cells. (A) Western blot analysis of the protein expression levels of Bcl-2, Bax, cleaved caspase-9, cleaved caspase-3 and caspase-3 in SH-SY5Y cells with different concentrations of GK treatment (12.5, 25 and 50 µg/ml) and reoxygenation for 1 h. (B) Quantity one software was used for quantitative analysis of Bax/Bcl-2 and optical density ratio of cascade protein bands normalized to tubulin. The results present averages of three independent experiments (mean ± SD). ^#P<0.001 vs. control group, *P<0.05 and **P<0.01 vs. OGD group. GK, ginkgolide K; OGD, oxygen-glucose deprivation.