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(a) Comparison of the blood group oligosaccharide-binding specificity of RSL and RSL[7FW]. Full names and chemical structures of the glycans are shown in Figure S11. (b) Docking of blood group B trisaccharide into the intermonomeric site of RSL[7FW] reveals nonfavorable short contacts between the fluorine atoms at Trp53 and Trp31 and the CH groups at positions C3 and C4 of galactose.
