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. 2018 Jul 5;18(3):2661–2668. doi: 10.3892/mmr.2018.9252

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Copyright: © Liu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — miR-665 is negatively associated with HOXA10. (A) The expression levels of miR-665 in ovarian cancer tissues (n=28) and normal ovarian tissues (n=15). Significantly lower expression of miR-665 was detected in ovarian cancer tissues compared with the normal ovarian tissues. (B) A plot of the relative expression of miR-665 vs. HOXA10 demonstrated an inverse correlation between the two parameters. The correlation index R² was calculated using the Spearman's rank test (R²=0.7496; P<0.01). The x-axis indicates the immunohistochemistry scores. The y-axis indicates the relative expression determined by reverse transcription-quantitative polymerase chain reaction (normalized to U6). **P<0.01. miR, microRNA; HOXA10, homeobox A10.